|
|
vitamin_K + H2O + a_protein_with_a_disulfide_bond <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + a_protein_with_reduced_L-cysteine_residues
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
M
|
|
BRENDA:
BR29366
MetaCyc:
1.1.4.1-RXN
|
|
|
|
vitamin_K + O2 + reduced_acceptor <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + H2O + acceptor
|
1.14.99.20
phylloquinone monooxygenase (2,3-epoxidizing)
|
–
|
|
|
BRENDA:
BR40389
KEGG:
R03510
MetaCyc:
1.14.99.20-RXN
|
|
|
|
peptidyl-4-carboxyglutamate + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + H+ + H2O <=> CO2 + peptidyl-glutamate + vitamin_KH2 + O2
|
4.1.1.90
peptidyl-glutamate 4-carboxylase
|
–
|
MK
|
|
BRENDA:
BR49124;
BS427500
KEGG:
R05144
MetaCyc:
RXN-10683
|
|
|
|
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + dithiothreitol <=> vitamin_K + oxidized_dithiothreitol
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
1.17.4.5
vitamin-K-epoxide reductase (warfarin-insensitive)
|
–
–
|
K
|
|
BRENDA:
BS188897
KEGG:
R03511
|
|
|
|
oxidized_dithiothreitol + 3-Hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone <=> dithiothreitol + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone
|
1.17.4.5
vitamin-K-epoxide reductase (warfarin-insensitive)
|
–
|
|
|
BRENDA:
BS188902
KEGG:
R03512
MetaCyc:
1.1.4.2-RXN
|
|
|
|
oxidized_dithiothreitol + 2-Hydroxy-vitamin_K <=> dithiothreitol + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone
|
1.17.4.5
vitamin-K-epoxide reductase (warfarin-insensitive)
|
–
|
|
|
KEGG:
R05830
MetaCyc:
RXN-19923
|
|
|
|
vitamin_K + electron_donor + O2 <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + oxidized_electron_donor + H2O
|
1.14.99.20
phylloquinone monooxygenase (2,3-epoxidizing)
|
–
|
|
|
BRENDA:
BS287933
|
|
|
|
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + reduced_dithiothreitol <=> vitamin_K_quinone + oxidized_dithiothreitol + H2O
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
BRENDA:
BS451419
|
|
|
|
vitamin_K + electron_donor + O2 <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + oxidized_electron + H2O
|
1.14.99.20
phylloquinone monooxygenase (2,3-epoxidizing)
|
–
|
|
|
BRENDA:
BS370240
|
|
|
|
peptidyl-L-glutamate + CO2 + O2 + vitamin_K <=> peptidyl-4-carboxy_L-glutamate + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + H2O
|
4.1.1.90
peptidyl-glutamate 4-carboxylase
|
–
|
|
|
BRENDA:
BS402835
|
|
|
|
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + thioredoxin <=> vitamin_K + thioredoxin_disulfide
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
BRENDA:
BS427885
|
|
|
|
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + oxidized_dithiothreitol <=> vitamin_K + dithiothreitol
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
BRENDA:
BS406877
|
|